Infectious Bovine Keratoconjunctivitis (IBK), also known as pinkeye, is a disease that has an important impact on the health and welfare of beef calves. In a project led by Veterinary Diagnostic & Production Animal Medicine Professor Annette O'Connor, Baker Center personnel (Lithio and Nettleton) are analyzing microbial community data collected from the eyes of calves prior to disease onset. Samples from the eyes of calves that subsequently develop the disease are compared to samples from the eyes of calves that remain disease free in a case-cohort study. Microbes that differ in abundance between the two types of samples are potential targets for the development of new pinkeye-prevention treatments.