 |
Computational and Systems Biology Summer Institute |
Research Projects for Fellows, 2009
P12: Analysis and prediction of B-cell and T-cell epitopes:
| Short Title: | Analysis and prediction of B-cell and T-cell epitopes: |
| Mentors: | PI: Vasant Honavar, Collaborator: Yasser El-Manzalawy, Graduate Students: Fadi Towfic, Raphael Jordan |
| Description: |
Computational methods for reliable identification of B-cell and T-cell epitopes are important for development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. We have develloped several machine learning methods for this problem. Ongoing work is focused on methods for identification conformational B-cell epitopes. |
| Web Resources: | |
| References: | http://ailab.cs.iastate.edu/bcpred/ http://ailab.cs.iastate.edu/mhcipreds/ |
| Suitable background skills: |