Computational and Systems Biology Summer Institute
Iowa State University

 We are interested in analyzing mRNA and proteomics and macromolecular complex data in the context of other available information to elucidate gene and protein networks that orchestrate specific biological processes. Our group has developed a database and associated tools for construction and refinement of gene networks from disparate datasets. These tools, is being used to construct models of gene and protein networks that control retinal differentiation. Work in progress is aimed at developing computational and statistical approaches to discovery of functional modules in gene and protein networks, and comparative analysis and integration of data from multiple experiments, multiple tissues, or multiple organisms.