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Computational and Systems Biology Summer Institute |
Research Projects for Fellows, 2009
P05: Hinges for Protein Dynamics
| Short Title: | Hinges for Protein Dynamics |
| Mentors: | Dr. Robert Jernigan, Mike Zimmerman |
| Description: |
The functional motions of many proteins correspond to simple hinges. But, understanding how these function in their atomic details is an unexplored subject. Do some atoms slide over others more readily than others? The intern is expected to be familiar with computational languages (FORTRAN is preferable). When there is a lack of knowledge, motivation and interest can substitute. |
| Web Resources: | http://www.molmovdb.org/ |
| References: | Atilgan AR , Durell SR, Jernigan RL, Demirel MC, Keskin O, Bahar I. , Anisotropy of fluctuation dynamics of proteins with an elastic network model, Biophysical Journal, 80(1):505-15, 2001 |
| Suitable background skills: |